TY - JOUR
T1 - Presence of plasma endotoxin is correlated with tumour necrosis factor receptor levels and disease activity in alcoholic cirrhosis
AU - Hanck, Christopher
AU - Rossol, Siegbert
AU - Böcker, Ulrich
AU - Tokus, Mehmet
AU - Singer, Manfred V.
PY - 1998
Y1 - 1998
N2 - Cytokines and plasma endotoxin were measured in a consecutive series of patients with alcoholic cirrhosis (AC). Endotoxaemia was found to be strongly correlated to increased plasma levels of functionally active tumour necrosis factor (TNF) receptors -p55 and -p75, TNF-α, and the Child-Pugh stage of the disease. Our data support the hypothesis of the pathogenic role of lipopolysaccharide in hepatocellular damage of patients with AC.
AB - Cytokines and plasma endotoxin were measured in a consecutive series of patients with alcoholic cirrhosis (AC). Endotoxaemia was found to be strongly correlated to increased plasma levels of functionally active tumour necrosis factor (TNF) receptors -p55 and -p75, TNF-α, and the Child-Pugh stage of the disease. Our data support the hypothesis of the pathogenic role of lipopolysaccharide in hepatocellular damage of patients with AC.
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U2 - 10.1093/alcalc/33.6.606
DO - 10.1093/alcalc/33.6.606
M3 - Article
C2 - 9872348
AN - SCOPUS:0031769233
SN - 0735-0414
VL - 33
SP - 606
EP - 608
JO - Alcohol and Alcoholism
JF - Alcohol and Alcoholism
IS - 6
ER -
